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Sources of bacteremia can be foci of chronic infection and invasive medical examinations. The risk of developing the disease is especially high with repeated massive bacteremia. With bacteremia St. aureus, infective endocarditis develops in almost 100% of cases. Significantly less virulence is found in epidermal staphylococcus, streptococci and pneumococci. Under certain conditions, adhesion of pathogenic bacteria to the endocardium occurs.